The mission of the GenABEL project is to provide a free framework for collaborative, robust, transparent, open-source based development of statistical genomics methodology. We aim to streamline methodology discussion, development, implementation, dissemination and maintenance; through the community.

The GenABEL suite (aka *ABEL suite) is practical result of implementation of statistical genomics methods developed in GenABEL project. The GenABEL suite is an umbrella name for a number of open-source software packages. The suite is

  • Rich in functionality. Many packages containing 100+ functions related to genomic analysis [ Packages ]
  • Efficient. Meaning you can run a genome-wide association scan on a netBook
  • Flexible. Programming your custom analysis is easy
  • Open, transparent, free. At present, all code is released under the GNU GPL [ GNU GPL ]
  • Well documented. More then 200 pages of reference manuals and about 300 pages of tutorials [ Tutorials | Manuals ]
  • Supported. By our community [ Forum ]
  • Collaborative. The community is open for your contribution [ Contribute ]

April 4, 2012: Course on consanguinity

Consanguinity, that is the practice to get married between closely related individuals, is still a common habit in many regions of the world. Within medical genetics, contemporary attention on consanguinity continues to be largely focused on rare autosomal recessive diseases. However, from an overall health perspective, consanguinity is a much wider and more complex topic involving major social, economic, and demographic influences. The main aim of the course is to enhance sharing of knowledge and promote research on the molecular and statistical genetics aspects of consanguinity.

July 12, 2011: Journal Club on statistical genomics open

Tue, 07/12/2011 - 22:48 — yurii
The “Journal Club on Statistical Genomics” (at forum.genabel.org) is an interactive platform which is created to help people working in statistical genomics to share and spread their theoretical knowledge.

July 2, 2011: Web-version of GenABEL manual updated

Sat, 07/02/2011 - 14:44 — yurii
Thanks to Anatoly Kirichenko, the web-version of the GenABEL package manual is updated to the current stable version 1.6-7.

June 18, 2011: GenABEL package 1.6-7 now considered current stable release

Sat, 06/18/2011 - 17:50 — yurii
Major updates compared to GenABEL package v. 1.6-5:

Added Xia Shen's function 'polygenic_hglm'. This procedure is functionally similar to 'polygenic', but is much faster and reports standard errors for fixed effects, which facilitates significance testing

March 22, 2011: 'findRelatives' in GenABEL-package

Tue, 03/22/2011 - 02:30 — yurii

'findRelatives' function is implemented in GenABEL-package development version. Compared to standard guessing of relationships from genomic kinship matrix, this procedure offers several enhancements

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